Chotsitsa cha Chomera

Chotsitsa cha Macleaya cordata

● Chotsitsa cha Macleaya cordata ndi chinthu chachilengedwe chochokera ku chomera cha poppy cha Macleaya cordata. Chili ndi ma alkaloid a benzophenanthridine ndipo chili ndi mphamvu zotsutsana ndi mabakiteriya, zotsutsana ndi kutupa, zotsutsana ndi tizilombo toyambitsa matenda, komanso zolimbikitsa kukula. Chimagwiritsidwa ntchito kwambiri m'magawo azachipatala, zowonjezera zakudya, mankhwala ophera tizilombo, komanso kafukufuku wamankhwala ndi chitukuko.

Dzina la Chinthu: Chotsitsa cha Macleaya cordata

Maonekedwe: Ufa wosalala wa lalanje kapena granular

Kuyika Kwachizolowezi: 25kg/ng'oma

Lumikizanani nafe

tsatanetsatane wa malonda

Mafotokozedwe Akatundu

kufotokozera1

kufotokozera2

Chidziwitso Choyambira

Dzina la Chinthu: Berberine hydrochloride

Maonekedwe: Ufa wachikasu wa kristalo

Fomula ya maselo: C20H18ClNO4

Kulemera kwa maselo: 372.822

Nambala ya CAS: [633-65-8]

Kuyika Kwachizolowezi: 25kg/ng'oma

Kusungunuka: Amasungunuka mosavuta m'madzi otentha, amasungunuka pang'ono m'madzi ozizira, ndipo sasungunuka kwambiri mu ethanol yozizira, chloroform, ndi ether.

Muyezo Wabwino: CP2020, JP, Yopangidwa ndi Makasitomala

Zosakaniza zazikulu zogwira ntchito

Zosakaniza zazikulu zomwe zimapezeka mu Boluohui ndi benzophenanthridine alkaloids, zomwe Sanguinarine ndi Chelerythrine zili ndi kuchuluka kwakukulu, zomwe zimapangitsa 50% ~ 80% ya ma alkaloids onse.

Dzina la Alkaloid	Fomula ya maselo	CAS	Kuchuluka kwa Zomwe Zili M'kati	Ntchito yaikulu
Sanguinarine	C₂₀H₁₄NO₄⁺	2447-54-3	30%~50%	Mankhwala oletsa mabakiteriya komanso oletsa tizilombo toyambitsa matenda
Chelerythrine	C₂₁H₁₈NO₄⁺	34316-15-9	20% ~ 40%	Wotsutsa kutupa komanso wotsutsa chotupa
Protopine	C₂₀H₁₉NO₅	130-86-9	5%~10%	Mankhwala ochepetsa ululu ndi oletsa kutupa
Allocryptopine	C₂₁H₂₃NO₅	485-91-6	3%~8%	antiarrhythmic

Zotsatira za mankhwala ndi mphamvu yake

1. Mankhwala opha tizilombo toyambitsa matenda osiyanasiyana

Njira yogwirira ntchito: imawononga nembanemba ya maselo a bakiteriya, imasokoneza kuchulukitsa kwa DNA

Matenda opatsirana pogonana:

Mabakiteriya a Gram-positive (Staphylococcus aureus, Streptococcus)

Bowa (Candida albicans)

Tizilombo toyambitsa matenda (coccidiosis, mphutsi zozungulira)

Matenda a m'mimba a nkhumba otchedwa spirochetes (kupewa ndi kuchiza matenda a m'mimba a nkhumba)

2. Kuletsa kutupa ndi chitetezo chamthupi

Kuletsa njira ya NF-κ B ndikuchepetsa kutulutsidwa kwa zinthu zotupa monga TNF-α ndi IL-6.

3. Mphamvu yolimbikitsira kukula (yogwiritsidwa ntchito ndi ziweto)

Kukweza thanzi la m'mimba mwa ziweto ndi nkhuku, kuonjezera kuchuluka kwa chakudya chomwe chimasinthidwa (kusintha maantibayotiki)

4. Ntchito Yotsutsana ndi Chotupa (Gawo Lofufuzira)

Kuyambitsa apoptosis ya maselo otupa (poyambitsa njira ya Caspase-3 ndi sanguinarine)

Minda Yofunsira Zobiriwira kwambiri

1. Mankhwala a ziweto ndi zowonjezera zakudya
Chakudya cha nkhumba/nkhuku (0.5-2g/kg) chopewera ndi kuchiza kutsegula m'mimba ndi coccidiosis
Kulima nsomba (kuletsa Vibrio, kupewa ndi kuchiza matenda a ndowe zoyera mu nkhanu)

2. Mankhwala ophera tizilombo
Mankhwala ophera tizilombo ochokera ku zomera (oletsa nsabwe za m'masamba ndi akangaude)

3. Kafukufuku ndi Chitukuko cha Mankhwala
Mankhwala ophera tizilombo toyambitsa matenda pakamwa (mankhwala a mano, otsukira pakamwa)
Mankhwala othandiza polimbana ndi chotupa

4. Zodzoladzola
Zosakaniza zochotsa ziphuphu (zoletsa Propionibacterium acnes)

Mayankho Ogwiritsira Ntchito

Zowonjezera Zakudya

Mankhwala osakaniza opanda maantibayotiki (alowa m'malo mwa 50% ya mankhwala opha tizilombo)

Kulamulira matenda a m'madzi (malo oletsa 18mm motsutsana ndi Aeromonas hydrophila)

Kupanga Mankhwala Ophera Tizilombo Toyambitsa Matenda

Fungiviti ya zipatso/masamba yachilengedwe (79% yoletsa nkhungu yoyera mkati mwa maola 72)

Chothandizira kuchiza mbewu (chimawonjezera kumera kwa mbeu ndi 15%)

Mankhwala Othandizira Pakati

Mankhwala oletsa khansa (mankhwala ochokera ku sanguinarine)

Mankhwala a mtima (kuletsa thrombosis)

Ntchito Zokongoletsa

Chotsukira pakamwa chachilengedwe (0.1%)

Seramu yochizira ziphuphu (1:5 yosakaniza ndi mafuta a mtengo wa tiyi)

Mlingo Wovomerezeka

● Chowonjezera cha chakudya: 50-150g/tani ya ziweto, 100-200g/tani ya ulimi wa nsomba

● Kugwiritsa ntchito mankhwala ophera tizilombo: Kusakaniza kwa 500-1000x kwa kupopera

Kusamalitsa

※ Kugwiritsa ntchito mankhwala kumafuna upangiri wa akatswiri

※ Pewani kuphatikiza ndi ma oxidant amphamvu

Chonde nditumizireni imelo ndipo mutha kupeza zambiri zomwe mukufuna.

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Chotsitsa cha Macleaya cordata

Zosakaniza zazikulu zogwira ntchito

Zotsatira za mankhwala ndi mphamvu yake

Minda Yofunsira Zobiriwira kwambiri